Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 3/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10757723 | 0.79 | DAO (0.59) | DAOKDM4EALDH1A1KMT2AHSD17B10 | |
| SCHEMBL11766114 | 0.77 | ALDH1A1 (0.51) | KDM4EMAOBALDH1A1RAB9AADORA1 | |
| SCHEMBL4308750 | 0.76 | L3MBTL1 (0.66) | KDM4EALDH1A1L3MBTL1KMT2AHSD17B10 | |
| SCHEMBL6382774 | 0.76 | DAO (0.65) | DAOKDM4ECASP1CASP7ALDH1A1 | |
| SCHEMBL9849536 | 0.75 | DAO (0.61) | DAOKDM4EMAOBALDH1A1LDHA | |
| SCHEMBL6172365 | 0.75 | SMN1; SMN2 (0.55) | DAOKDM4EMAOBALDH1A1RAB9A | |
| SCHEMBL18523561 | 0.75 | HTR4 (0.43) | DAOKDM4EMAOBALDH1A1RAB9A | |
| SCHEMBL7163743 | 0.74 | KDM4E (0.52) | DAOKDM4EALDH1A1FEN1KMT2A | |
| SCHEMBL9498048 | 0.74 | KDM4E (0.52) | DAOKDM4EFEN1KMT2A | |
| SCHEMBL10677691 | 0.74 | KDM4E (0.52) | DAOKDM4ECASP1CASP7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240859-B1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1993-04-28 | — | — | EP | disclosed |