Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.98 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.98 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.98 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.98 |
| ▸ | MEN1 | O00255 | 1/20 | 0.98 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.98 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.98 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.96 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120938 | 1.00 | ADORA3 (0.98) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL17808982 | 1.00 | ADORA3 (0.98) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL4803030 | 1.00 | ADORA3 (0.98) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL2492838 | 0.99 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL12264514 | 0.99 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL472609 | 0.99 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL3950346 | 0.99 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL2461163 | 0.99 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL19807522 | 0.99 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL29354999 | 0.99 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253962-B1 | USE OF ADENOSINE DERIVATIVES AS ANTI-DEMENTIA AGENTS | HOECHST JAPAN LIMITED (JP) | 1993-03-24 | — | — | EP | disclosed |