Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498627 | 1.00 | PPARG (0.40) | PPARGSOAT1PTPN1PTPN11CYSLTR2 | |
| SCHEMBL9500815 | 1.00 | PPARG (0.40) | PPARGSOAT1PTPN1PTPN11CYSLTR2 | |
| SCHEMBL9498407 | 1.00 | PPARG (0.40) | PPARGSOAT1PTPN1PTPN11CYSLTR2 | |
| SCHEMBL9499996 | 1.00 | PPARG (0.40) | PPARGSOAT1PTPN1PTPN11CYSLTR2 | |
| SCHEMBL9498511 | 0.99 | PTPN1 (0.39) | PPARGSOAT1PTPN1PTPN11CYSLTR2 | |
| SCHEMBL9500229 | 0.95 | ROCK2 (0.39) | PPARGSOAT1PTPN1NPC1RAB9A | |
| SCHEMBL9500367 | 0.91 | ROCK2 (0.36) | PPARGNPC1RAB9ASMN1; SMN2CDC7 | |
| SCHEMBL9502130 | 0.86 | ROCK2 (0.38) | THRBROCK2ROCK1 | |
| SCHEMBL9500250 | 0.86 | PPARG (0.42) | PPARGSOAT1PTPN1PTPN11CYSLTR2 | |
| SCHEMBL9869383 | 0.86 | PPARG (0.42) | PPARGSOAT1PTPN1PTPN11CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |