Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500229 | 0.93 | ROCK2 (0.39) | ROCK2ROCK1LMNAACACBALDH1A1 | |
| SCHEMBL9498511 | 0.92 | PTPN1 (0.39) | ROCK2ROCK1LMNACDC7PLK4 | |
| SCHEMBL9500815 | 0.91 | PPARG (0.40) | ROCK2ROCK1CDC7PLK4CHEK1 | |
| SCHEMBL9499996 | 0.91 | PPARG (0.40) | ROCK2ROCK1CDC7PLK4CHEK1 | |
| SCHEMBL9499042 | 0.91 | PPARG (0.40) | ROCK2ROCK1CDC7PLK4CHEK1 | |
| SCHEMBL9498627 | 0.91 | PPARG (0.40) | ROCK2ROCK1CDC7PLK4CHEK1 | |
| SCHEMBL9498407 | 0.91 | PPARG (0.40) | ROCK2ROCK1CDC7PLK4CHEK1 | |
| SCHEMBL9502130 | 0.90 | ROCK2 (0.38) | ROCK2ROCK1LMNAACACBALDH1A1 | |
| SCHEMBL9498247 | 0.86 | ALOX5AP (0.41) | ROCK2ROCK1LMNAMAP4K4FYN | |
| SCHEMBL9501989 | 0.85 | LMNA (0.38) | ROCK2ROCK1LMNAACACBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |