SCHEMBL9499050

SCHEMBL9499050

CCCCOCCCC(=O)Oc1ccc(C(=O)Nc2cccc(Cl)c2Cl)cc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.49
▸ KMT2A Q03164 5/20 0.49
▸ LMNA P02545 4/20 0.49
▸ NPC1 O15118 4/20 0.49
▸ RAB9A P51151 4/20 0.49
▸ MEN1 O00255 3/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.49
▸ HPGD P15428 1/20 0.49
▸ POLB P06746 1/20 0.47
▸ PLK1 P53350 2/20 0.45
▸ GAA P10253 1/20 0.44
▸ TDP1 Q9NUW8 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.43
▸ ELANE P08246 1/20 0.41
▸ PRTN3 P24158 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ NR1H4 Q96RI1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11146339 0.86 PLK1 (0.55) MAPTKMT2ALMNANPC1RAB9A
SCHEMBL11146334 0.84 MAPT (0.54) MAPTKMT2ALMNANPC1RAB9A
SCHEMBL11193309 0.84 PLK1 (0.60) MAPTKMT2ALMNANPC1RAB9A
SCHEMBL11319357 0.81 PLK1 (0.66) MAPTKMT2ALMNANPC1RAB9A
SCHEMBL11149361 0.80 MAPT (0.54) MAPTKMT2ALMNANPC1RAB9A
SCHEMBL9621389 0.80 MAPT (0.68) MAPTKMT2ALMNANPC1RAB9A
SCHEMBL11308434 0.80 MGLL (0.56) MAPTKMT2ALMNANPC1RAB9A
SCHEMBL11151339 0.79 MAPT (0.55) MAPTKMT2ALMNANPC1RAB9A
SCHEMBL11308435 0.79 MAPT (0.49) MAPTKMT2ALMNANPC1RAB9A
SCHEMBL9495874 0.78 KMT2A (0.71) MAPTKMT2ALMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5227511-A Agriculture, horticulture, dwarfing, stem development HODOGAYA CHEMICAL CO., LTD. (JP) 1993-07-13 — — US disclosed
EP-0374736-B1 BENZAMIDE DERIVATIVES AND PLANT GROWTH REGULANTS CONTAINING THEM HODOGAYA CHEMICAL CO., LTD. (JP) 1993-03-24 — — EP disclosed
US-5043006-A Benzamide derivatives and plant growth regulants containing them HODOGAYA CHEMICAL CO., LTD. (JP) 1991-08-27 — — US disclosed
Send feedback