SCHEMBL9499124

SCHEMBL9499124

CCOC(=O)CCCCCCC1C(=O)C=CC1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
ALOX15 P16050 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
USP2 O75604 1/20 0.50
PPARG P37231 2/20 0.47
PPARD Q03181 1/20 0.47
PPARA Q07869 1/20 0.47
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TRPA1 O75762 2/20 0.41
NR4A2 P43354 2/20 0.41
CYP1A2 P05177 1/20 0.40
NLRP3 Q96P20 1/20 0.40
CYP4F2 P78329 1/20 0.40
CYP4A11 Q02928 1/20 0.40
DNTT P04053 1/20 0.38
TBXAS1 P24557 1/20 0.38
NR1I2 O75469 1/20 0.37
PGR P06401 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9497680 0.85 PTGER2 (0.46) ALDH1A1TDP1PPARGPPARDPPARA
SCHEMBL9495622 0.84 PTGER2 (0.44) ALDH1A1TDP1PPARGPPARDPPARA
SCHEMBL11867271 0.83 ALDH1A1 (0.45) ALDH1A1ALOX15TDP1USP2PPARG
SCHEMBL11867277 0.83 ALDH1A1 (0.45) ALDH1A1ALOX15TDP1USP2PPARG
SCHEMBL11867281 0.83 ALDH1A1 (0.45) ALDH1A1ALOX15TDP1USP2PPARG
SCHEMBL15481309 0.82 ALDH1A1 (0.44) ALDH1A1ALOX15TDP1USP2PPARG
SCHEMBL11307002 0.81 PPARG (0.36) ALDH1A1ALOX15TDP1USP2PPARG
SCHEMBL10973865 0.80 PPARG (0.59) TDP1PPARGPPARDPPARATSHR
SCHEMBL11861462 0.80 TRPA1 (0.43) ALDH1A1ALOX15TDP1USP2PPARG
SCHEMBL11863889 0.80 TRPA1 (0.50) ALDH1A1ALOX15TDP1USP2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0247620-B1 PRODUCTION OF CYCLOPENTENONES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-05 EP disclosed
US-4957867-A Production of cyclopentenones by enzyme resolution SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-09-18 US disclosed
EP-0247620-A2 Production of cyclopentenones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-12-02 EP disclosed
US-4076732-A Derivatives of α-(6-carboxyhexyl) furfuryl alcohol AMERICAN CYANAMID COMPANY (US) 1978-02-28 US disclosed