Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9501096 | 0.99 | SLC6A4 (0.64) | SLC6A4HRH3SLC6A2SLC6A9 | |
| Formic Acid SCHEMBL9638472 | 0.92 | SLC6A4 (0.57) | SLC6A4HRH3SLC6A9 | |
| SCHEMBL7158810 | 0.86 | SLC6A4 (0.73) | SLC6A4HRH3SLC6A2SLC6A9 | |
| Bromide SCHEMBL9499379 | 0.85 | SLC6A4 (0.61) | SLC6A4HRH3SLC6A2SLC6A9 | |
| SCHEMBL9502684 | 0.84 | SLC6A4 (0.70) | SLC6A4HRH3SLC6A2SLC6A9 | |
| SCHEMBL5270870 | 0.84 | SLC6A4 (0.70) | SLC6A4HRH3SLC6A2SLC6A9 | |
| SCHEMBL685134 | 0.84 | SLC6A4 (0.70) | SLC6A4HRH3SLC6A2SLC6A9 | |
| SCHEMBL4785426 | 0.82 | SLC6A4 (0.68) | SLC6A4HRH3SLC6A2SLC6A9 | |
| SCHEMBL10913184 | 0.82 | SLC6A4 (0.68) | SLC6A4HRH3SLC6A2SLC6A9 | |
| SCHEMBL9500943 | 0.82 | SLC6A4 (0.68) | SLC6A4HRH3SLC6A2SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336753-B1 | IMPROVEMENTS IN OR RELATING TO PROPANAMINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1992-07-08 | — | — | EP | claimed |
| EP-0336753-A1 | Improvements in or relating to propanamine derivatives | ELI LILLY AND COMPANY (US) | 1989-10-11 | — | — | EP | claimed |
| US-5238959-A | For inhibiting serotonin uptake, antidepressant, suppression of alcoholism and obesity | ELI LILLY AND COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0336753-B1 | IMPROVEMENTS IN OR RELATING TO PROPANAMINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1992-07-08 | — | — | EP | disclosed |
| EP-0336753-A1 | Improvements in or relating to propanamine derivatives | ELI LILLY AND COMPANY (US) | 1989-10-11 | — | — | EP | disclosed |