Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 16/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9496913 | 0.91 | MAPT (0.47) | ACACBMCHR1MAPTRAB9AL3MBTL1 | |
| SCHEMBL9498375 | 0.90 | MAPT (0.52) | ACACBMAPTRAB9AL3MBTL1 | |
| SCHEMBL9496197 | 0.90 | ACACB (0.51) | ACACBMCHR1MAPTL3MBTL1 | |
| SCHEMBL9497236 | 0.89 | MAPT (0.51) | ACACBMAPTRAB9AL3MBTL1 | |
| SCHEMBL9496177 | 0.88 | MCHR1 (0.47) | ACACBMCHR1 | |
| SCHEMBL9495908 | 0.88 | MCHR1 (0.49) | ACACBMCHR1 | |
| SCHEMBL9497382 | 0.87 | NAAA (0.44) | ACACBMCHR1RAB9AL3MBTL1 | |
| SCHEMBL9497131 | 0.86 | NAAA (0.46) | ACACBMCHR1L3MBTL1 | |
| SCHEMBL9495348 | 0.86 | NAAA (0.46) | ACACBMCHR1L3MBTL1 | |
| SCHEMBL9495438 | 0.86 | NAAA (0.46) | ACACBMCHR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |