SCHEMBL94997

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27621550	0.77	ALDH1A1 (0.60)	SGK1MCL1ACLYTDP1POLB
	SCHEMBL14721124	0.74	MCL1 (0.47)	SGK1MCL1ACLYMAPTCCR2
	SCHEMBL4615405	0.74	SGK1 (0.48)	SGK1MCL1ACLYMAPTCCR2
	SCHEMBL96179	0.72	ATM (0.55)	MAPTTSHRPOLBGAAGFER
	SCHEMBL15882311	0.72	ACLY (0.50)	SGK1MCL1ACLYCCR2TSHR
	SCHEMBL5653065	0.72	MEN1 (0.49)	SGK1MCL1ACLYMAPTCCR2
	SCHEMBL6097407	0.72	MCL1 (0.45)	SGK1MCL1ACLYCCR2TSHR
	SCHEMBL94670	0.71	GAA (0.71)	MAPTTSHRPOLBGAAGFER
	SCHEMBL2303572	0.71	RXFP1 (0.62)	SGK1MCL1ACLYCCR2L3MBTL1
	SCHEMBL4829257	0.70	SGK1 (0.45)	SGK1MCL1ACLYMAPTCCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.