Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9497834 | 0.90 | CA12 (0.41) | ALDH1A1MEN1KMT2ATSHRHRH3 | |
| SCHEMBL9501651 | 0.90 | CA12 (0.41) | ALDH1A1MEN1KMT2ATSHRHRH3 | |
| SCHEMBL9795556 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ATSHRTDP1 | |
| SCHEMBL9795265 | 0.80 | GAA (0.43) | GAAALDH1A1MEN1KMT2ATDP1 | |
| Cyclohexanol SCHEMBL9499559 | 0.79 | EPHX1 (0.52) | GAAEPHX1ALDH1A1TSHRTDP1 | |
| Fumaric Acid SCHEMBL9795313 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ATSHRTDP1 | |
| SCHEMBL166433 | 0.77 | TDP1 (0.58) | GAAALDH1A1TSHRTDP1LMNA | |
| SCHEMBL9497701 | 0.77 | CYP2D6 (0.40) | EPHX1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5657522 | 0.76 | GLA (0.58) | GAAALDH1A1TSHRTDP1LMNA | |
| SCHEMBL9499995 | 0.75 | CYP2D6 (0.38) | EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367019-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING NITROXYALKYL AMINE WITH AN AMIDE FUNCTION, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1993-05-12 | — | — | EP | disclosed |