Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795073 | 0.89 | TMEM97 (0.38) | GAAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9795139 | 0.88 | CA12 (0.39) | GAAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9795556 | 0.83 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL9499990 | 0.80 | GAA (0.44) | GAAL3MBTL1ALDH1A1KMT2AMEN1 | |
| Fumaric Acid SCHEMBL9795313 | 0.78 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL9795057 | 0.77 | EPHX2 (0.33) | — | |
| SCHEMBL9795185 | 0.75 | KEAP1 (0.36) | — | |
| SCHEMBL14223309 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KMT2ATDP1POLBSMN1; SMN2 | |
| SCHEMBL9795196 | 0.74 | DGAT1 (0.36) | L3MBTL1ALDH1A1POLBLMNADGAT1 | |
| SCHEMBL9795301 | 0.73 | TDP1 (0.39) | GAAL3MBTL1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |