⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844330 | 0.79 | LMNA (0.42) | — | |
| SCHEMBL9737144 | 0.75 | CYP19A1 (0.40) | — | |
| SCHEMBL761160 | 0.72 | — | — | |
| SCHEMBL14332945 | 0.71 | LMNA (0.44) | — | |
| SCHEMBL7837590 | 0.69 | LMNA (0.52) | — | |
| SCHEMBL10506391 | 0.68 | LMNA (0.55) | — | |
| SCHEMBL20711975 | 0.65 | LMNA (0.48) | — | |
| SCHEMBL22513576 | 0.62 | LMNA (0.46) | — | |
| Hydrochloric Acid SCHEMBL247629 | 0.62 | LMNA (1.00) | — | |
| SCHEMBL9746578 | 0.62 | LMNA (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12628827-B2 | Isoxazoline compounds and their use as pest control agents | PI INDUSTRIES LIMITED (IN) | 2026-05-19 | — | — | US | disclosed |
| US-20250387391-A1 | A SOLUBLE GUANYLAT CYCLASE ACTIVATOR FOR TREATING CHRONIC VASCULAR DYSFUNCTION | UNIV BERLIN CHARITE (DE) | 2025-12-25 | — | — | US | disclosed |
| US-20250129048-A1 | MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER INC. (US) | 2025-04-24 | — | — | US | disclosed |
| US-20240057604-A1 | ISOXAZOLINE COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI INDUSTRIES LTD. (IN) | 2024-02-22 | — | — | US | disclosed |
| WO-2023002965-A1 | SALT OF HETEROCYCLIC COMPOUND WITH ANTI-MALARIA ACTIVITY, AND CRYSTALS THEREOF | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2023-01-26 | — | — | WO | disclosed |
| CN-111732594-B | Preparation method of fluxaparide | 苏州富士莱医药股份有限公司 | 2022-03-04 | — | — | CN | disclosed |
| WO-2022036940-A1 | PREPARATION METHOD FOR FLUZOPARIB | 苏州富士莱医药股份有限公司 | 2022-02-24 | — | — | WO | disclosed |
| CN-111732594-A | Preparation method of fluxaparide | 苏州富士莱医药股份有限公司 | 2020-10-02 | — | — | CN | disclosed |
| CN-108658816-A | Trifluoroethyl sulfide derivatives as the substitution of the N- aryl amidines of acaricide and insecticide | 拜尔农作物科学股份公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-108276358-A | Trifluoroethyl sulfide derivatives as the substitution of the N- aryl amidines of acaricide and insecticide | 拜尔农作物科学股份公司 | 2018-07-13 | — | — | CN | disclosed |
| US-5138069-A | Treating hypertension and congestive heart failure | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-11 | — | — | US | disclosed |
| US-5128355-A | Hypotensive | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0479892-A1 | FUSED-RING ARYL SUBSTITUTED IMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-15 | — | — | EP | disclosed |
| EP-0479903-A1 | SUBSTITUTED IMIDAZOLES. | DU PONT (US) | 1992-04-15 | — | — | EP | disclosed |
| WO-1991000277-A1 | SUBSTITUTED IMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-10 | — | — | WO | disclosed |
| WO-1991000281-A2 | FUSED-RING ARYL SUBSTITUTED IMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-10 | — | — | WO | disclosed |
| CN-1040197-A | SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES | DU PONT (US) | 1990-03-07 | — | — | CN | disclosed |
| EP-0324377-A2 | Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSaids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-19 | — | — | EP | disclosed |
| WO-1989006233-A1 | ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLES AND COMBINATIONS THEREOF WITH DIURETICS AND NSAIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-13 | — | — | WO | disclosed |
| EP-0253310-A2 | Angiotensin II receptor blocking imidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |