Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10547542 | 0.85 | CETP (0.41) | CETPHTTTSHRMAPK1MEN1 | |
| SCHEMBL10694157 | 0.82 | CHKA (0.41) | MAPT | |
| SCHEMBL11478430 | 0.79 | HDAC6 (0.46) | HTTMEN1GAAMAPTKMT2A | |
| SCHEMBL8402798 | 0.76 | HTT (0.42) | CETPHTTMAPK1MEN1GAA | |
| SCHEMBL11480911 | 0.76 | HTT (0.42) | CETPHTTMAPK1MEN1GAA | |
| SCHEMBL8626864 | 0.76 | CYP3A4 (0.55) | CETPTSHRMAPK1MAPTTAAR1 | |
| SCHEMBL6506855 | 0.76 | CETP (0.49) | CETPTSHRMAPK1MEN1GAA | |
| SCHEMBL10931233 | 0.76 | NFE2L2 (0.39) | CETPMAPK1KMT2ATAAR1HTR2A | |
| SCHEMBL11784122 | 0.75 | KIF11 (0.44) | — | |
| SCHEMBL171829 | 0.75 | TSHR (0.48) | CETPTSHRMAPK1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322279-B1 | PROCESS FOR THE ACYLATION OF N,N-DIALLYL ANILINE | RHONE-POULENC CHIMIE (FR) | 1993-04-14 | — | — | EP | disclosed |
| US-4946983-A | USING CARBOXYLIC ACID HALIDE | RHONE-POULENC CHIMIE (FR) | 1990-08-07 | — | — | US | disclosed |
| EP-0378463-A1 | Process for the desallylation of N-allylanilines and N,N-diallylanilines with metals | RHONE-POULENC CHIMIE (FR) | 1990-07-18 | — | — | EP | disclosed |
| EP-0322279-A2 | Process for the acylation of N,N-diallyl aniline | RHONE-POULENC CHIMIE (FR) | 1989-06-28 | — | — | EP | disclosed |