Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 10/20 | 0.57 |
| ▸ | BCHE | P06276 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22911500 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2HTTACHEBCHELMNA | |
| SCHEMBL8302733 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2HTTACHEBCHELMNA | |
| SCHEMBL12778520 | 0.83 | LMNA (0.61) | SMN1; SMN2HTTACHEBCHELMNA | |
| SCHEMBL356804 | 0.80 | ACHE (0.63) | SMN1; SMN2HTTACHEBCHELMNA | |
| SCHEMBL29654960 | 0.80 | ACHE (0.63) | SMN1; SMN2HTTACHEBCHELMNA | |
| SCHEMBL14200361 | 0.80 | LMNA (0.58) | SMN1; SMN2HTTACHEBCHELMNA | |
| SCHEMBL10630262 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2HTTACHEBCHELMNA | |
| SCHEMBL31039479 | 0.80 | LMNA (0.62) | SMN1; SMN2HTTACHEBCHELMNA | |
| SCHEMBL14200146 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2HTTACHEBCHELMNA | |
| Hydrochloric Acid SCHEMBL10493571 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2HTTACHEBCHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347305-B1 | [(Aryl-4-piperazinyl-1)-2-ethoxy]-3 p cymene, the ortho-, meta-, para-monosubstituted or disubstituted phenyl ring derivatives, process for their preparation and medicaments containing the same as the active principle | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) Société à responsabilité limitée dite: (FR) | 1993-05-12 | — | — | EP | claimed |
| US-5110816-A | Urogenital disorders | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) (FR) | 1992-05-05 | — | — | US | disclosed |