SCHEMBL9500087

SCHEMBL9500087

C=CCc1ccc(C(C)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
CYP3A4 P08684 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
TP53 P04637 1/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
ALOX12 P18054 1/20 0.46
PTGS2 P35354 1/20 0.43
CNR2 P34972 2/20 0.40
PPARG P37231 2/20 0.38
PPARD Q03181 2/20 0.38
PPARA Q07869 1/20 0.38
CYP2C19 P33261 1/20 0.38
XDH P47989 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAOB P27338 1/20 0.37
TAAR1 Q96RJ0 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9578892 0.92 ALDH1A1 (0.52) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL9630714 0.84 CYP3A4 (0.44) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Allylbenzene SCHEMBL793935 0.82 PTGS2 (0.44) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Allylbenzene SCHEMBL17500025 0.81 PTGS2 (0.47) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL7193434 0.79 ALDH1A1 (0.52) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Allylbenzene SCHEMBL821993 0.78 SLC6A2 (0.50) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Allylbenzene SCHEMBL29084614 0.78 MAOB (0.46) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Allylbenzene SCHEMBL10325179 0.76 MAOB (0.60) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Allylbenzene SCHEMBL2478260 0.76 MAOB (0.60) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Allylbenzene SCHEMBL21274 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5200261-A FOAM MATERIAL REINFORCED WITH COMPOSITE FIBERS TORAY INDUSTRIES, INC. (JP) 1993-04-06 US disclosed
EP-0432997-A2 Fiber-reinforced foamed material and method of producing it TORAY INDUSTRIES, INC. (JP) 1991-06-19 EP disclosed