Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500276 | 0.99 | KDM4E (0.43) | LTA4HKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9499201 | 0.99 | KDM4E (0.43) | LTA4HKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9498606 | 0.99 | KDM4E (0.43) | LTA4HKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9498386 | 0.99 | KDM4E (0.43) | LTA4HKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9498427 | 0.99 | KDM4E (0.43) | LTA4HKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9500172 | 0.97 | CYP2D6 (0.40) | LTA4HKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9498372 | 0.92 | CYP4F2 (0.38) | LTA4HKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9499159 | 0.88 | MAPT (0.38) | LTA4HKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9499324 | 0.85 | LTA4H (0.40) | LTA4HKDM4EPTPN11NR5A1PDK2 | |
| SCHEMBL9498220 | 0.84 | CYP11B1 (0.38) | ALDH1A1HPGDHTTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |