Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498372 | 0.91 | CYP4F2 (0.38) | MAPTKDM4ENPC1MAPK1LTA4H | |
| SCHEMBL9500172 | 0.91 | CYP2D6 (0.40) | MAPTKDM4ENPC1LTA4HKMT2A | |
| SCHEMBL9498220 | 0.90 | CYP11B1 (0.38) | NPC1MAPK1MEN1KMT2ARAB9A | |
| SCHEMBL9500255 | 0.88 | LTA4H (0.41) | MAPTKDM4ENPC1LTA4HRAB9A | |
| SCHEMBL9499201 | 0.87 | KDM4E (0.43) | MAPTKDM4ENPC1LTA4HSMN1; SMN2 | |
| SCHEMBL9500276 | 0.87 | KDM4E (0.43) | MAPTKDM4ENPC1LTA4HSMN1; SMN2 | |
| SCHEMBL9498427 | 0.87 | KDM4E (0.43) | MAPTKDM4ENPC1LTA4HSMN1; SMN2 | |
| SCHEMBL9498386 | 0.87 | KDM4E (0.43) | MAPTKDM4ENPC1LTA4HSMN1; SMN2 | |
| SCHEMBL9498606 | 0.87 | KDM4E (0.43) | MAPTKDM4ENPC1LTA4HSMN1; SMN2 | |
| SCHEMBL9502022 | 0.82 | CCR1 (0.44) | NPC1MAPK1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |