Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500468 | 0.96 | PPARG (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9500333 | 0.95 | PPARG (0.42) | CYP2D6NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9498257 | 0.95 | PPARG (0.42) | CYP2D6NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9499035 | 0.95 | PPARG (0.42) | CYP2D6NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9869383 | 0.95 | PPARG (0.42) | CYP2D6NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9500250 | 0.95 | PPARG (0.42) | CYP2D6NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9501989 | 0.93 | LMNA (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9500781 | 0.89 | MAPT (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9500229 | 0.85 | ROCK2 (0.39) | CYP2C9CYP2C19CYP19A1CYP1A2CYP2D6 | |
| SCHEMBL9500050 | 0.85 | CYP2A6 (0.44) | NPC1L3MBTL1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |