Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.33 |
| ▸ | GABRP | O00591 | 5/20 | 0.33 |
| ▸ | GABRD | O14764 | 5/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.33 |
| ▸ | GABRE | P78334 | 5/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9221073 | 1.00 | PLAU (0.34) | PLAUGABRB3GABRPGABRDGABRA1 | |
| SCHEMBL9215567 | 0.87 | GABRB3 (0.34) | PLAUGABRB3GABRPGABRDGABRA1 | |
| SCHEMBL9501595 | 0.87 | GABRB3 (0.34) | PLAUGABRB3GABRPGABRDGABRA1 | |
| SCHEMBL9218454 | 0.77 | MAPT (0.40) | PLAUGABRB3GABRPGABRDGABRA1 | |
| SCHEMBL9501521 | 0.77 | MAPT (0.40) | PLAUGABRB3GABRPGABRDGABRA1 | |
| SCHEMBL9501578 | 0.76 | GABRB3 (0.36) | PLAUGABRB3GABRPGABRDGABRA1 | |
| SCHEMBL9216648 | 0.76 | GABRB3 (0.36) | PLAUGABRB3GABRPGABRDGABRA1 | |
| SCHEMBL9219343 | 0.72 | GABRA2 (0.40) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9213839 | 0.72 | GABRB3 (0.41) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9208952 | 0.71 | GABRB3 (0.35) | GABRB3GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189053-A | Insecticide, acaricide and endoparasiticide | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-02-23 | — | — | US | disclosed |
| US-5109012-A | 2-IMIDAZOL(IN)E SUBSTITUTED ARYL-1,2,3-TRIAZOLE PESTICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |