Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 3/20 | 0.32 |
| ▸ | F2 | P00734 | 4/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 2/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498640 | 1.00 | EPHX1 (0.40) | EPHX1DPP4DPP7KDM1ACTSC | |
| SCHEMBL9500909 | 1.00 | EPHX1 (0.40) | EPHX1DPP4DPP7KDM1ACTSC | |
| SCHEMBL9500871 | 0.97 | EPHX1 (0.42) | EPHX1DPP4DPP7KDM1ACTSC | |
| SCHEMBL9500623 | 0.94 | EPHX1 (0.39) | EPHX1DPP4DPP7KDM1ACTSC | |
| SCHEMBL9500859 | 0.88 | EPHX1 (0.39) | EPHX1DPP4DPP7KDM1ACTSC | |
| SCHEMBL9498926 | 0.86 | LAP3 (0.40) | DPP4DPP7LTA4HLAP3ANPEP | |
| SCHEMBL9499490 | 0.80 | CYP3A4 (0.43) | KDM1AF2KMT2A | |
| SCHEMBL9500880 | 0.73 | CYP3A4 (0.42) | KDM1AF2KMT2A | |
| SCHEMBL9499459 | 0.73 | CYP3A4 (0.42) | KDM1AF2KMT2A | |
| SCHEMBL9500612 | 0.73 | LAP3 (0.42) | EPHX1CTSCLTA4HGRM4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333000-B1 | PEPTIDES WITH INHIBITORY ACTIVITY OF ENZYMATIC SYSTEMS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1993-05-19 | — | — | EP | disclosed |