Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 7/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500909 | 0.97 | EPHX1 (0.40) | EPHX1F2CTSCDPP4DPP7 | |
| SCHEMBL9500554 | 0.97 | EPHX1 (0.40) | EPHX1F2CTSCDPP4DPP7 | |
| SCHEMBL9498640 | 0.97 | EPHX1 (0.40) | EPHX1F2CTSCDPP4DPP7 | |
| SCHEMBL9500623 | 0.93 | EPHX1 (0.39) | EPHX1F2CTSCDPP4DPP7 | |
| SCHEMBL9500859 | 0.87 | EPHX1 (0.39) | EPHX1F2CTSCDPP4DPP7 | |
| SCHEMBL9498926 | 0.82 | LAP3 (0.40) | DPP4DPP7MME | |
| SCHEMBL9499490 | 0.77 | CYP3A4 (0.43) | F2KMT2AKDM1A | |
| SCHEMBL9498619 | 0.74 | LAP3 (0.42) | EPHX1CTSCITGB1ITGA4 | |
| SCHEMBL9500894 | 0.74 | LAP3 (0.42) | EPHX1CTSCITGB1ITGA4 | |
| SCHEMBL9500536 | 0.74 | LAP3 (0.42) | EPHX1CTSCITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333000-B1 | PEPTIDES WITH INHIBITORY ACTIVITY OF ENZYMATIC SYSTEMS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1993-05-19 | — | — | EP | disclosed |
| US-5145872-A | PEPTIDES WITH PHARMACEUTICAL ACTIVITY | ZAMBON GROUP, S.P.A. (IT) | 1992-09-08 | — | — | US | disclosed |
| EP-0333000-A2 | Peptides with inhibitory activity of enzymatic systems, process for their preparation and pharmaceutical compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1989-09-20 | — | — | EP | disclosed |