SCHEMBL950068

SCHEMBL950068

ClC=CCC=CCOCC=CCC=CCl

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27833568 0.81
SCHEMBL27833554 0.81
SCHEMBL423889 0.81
SCHEMBL3763742 0.71 PTGS1 (0.36) PTGS1
SCHEMBL27654786 0.71 PTGS1 (0.36) PTGS1
SCHEMBL1444842 0.71 PTGS1 (0.32) PTGS1
SCHEMBL3263988 0.71 PTGS1 (0.32) PTGS1
SCHEMBL8517761 0.69
SCHEMBL11056456 0.67
SCHEMBL8938890 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2451765-B1 PROCESS FOR THE MANUFACTURE OF HALOGENATED PRECURSORS OF ALKENONES UNDER SPECIFIC CONDITIONS SOLVAY (BE) 2016-12-28 EP disclosed
EP-2451763-B1 PROCESS FOR THE MANUFACTURE OF HALOGENATED PRECURSORS OF ALKENONES IN THE PRESENCE OF A SOLVENT SOLVAY (BE) 2015-03-04 EP disclosed
US-8957254-B2 Process for chemical synthesis from an alkenone made from a halogenated precursor SOLVAY SA (BE) 2015-02-17 US disclosed
US-20140051892-A1 Process for chemical synthesis from an alkenone made from a halogenated precursor SOLVAY SA (BE) 2014-02-20 US disclosed
US-8552221-B2 Process for the manufacture of halogenated precursors of alkenones under specific conditions SOLVAY SA (BE) 2013-10-08 US disclosed
US-8426650-B2 Process for the manufacture of halogenated precursors of alkenones in the presence of a solvent SOLVAY SA (BE) 2013-04-23 US disclosed
EP-2451763-A1 PROCESS FOR THE MANUFACTURE OF HALOGENATED PRECURSORS OF ALKENONES IN THE PRESENCE OF A SOLVENT SOLVAY SA (BE) 2012-05-16 EP disclosed
EP-2451765-A1 PROCESS FOR THE MANUFACTURE OF HALOGENATED PRECURSORS OF ALKENONES UNDER SPECIFIC CONDITIONS SOLVAY SA (BE) 2012-05-16 EP disclosed
US-20120116128-A1 Process For The Manufacture Of Halogenated Precursors Of Alkenones In The Presence Of A Solvent SOLVAY SA (BE) 2012-05-10 US disclosed
US-20120101305-A1 Process For The Manufacture Of Halogenated Precursors Of Alkenones Under Specific Conditions SOLVAY SA (BE) 2012-04-26 US disclosed
WO-2011003856-A1 PROCESS FOR THE MANUFACTURE OF HALOGENATED PRECURSORS OF ALKENONES UNDER SPECIFIC CONDITIONS SOLVAY SA (BE) 2011-01-13 WO disclosed
WO-2011003854-A1 PROCESS FOR THE MANUFACTURE OF HALOGENATED PRECURSORS OF ALKENONES IN THE PRESENCE OF A SOLVENT SOLVAY SA (BE) 2011-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120101305-A1 Process For The Manufacture Of Halogenated Precursors Of Alkenones Under Specific Conditions HSD11B2, HSD17B12, HSD11B1 PTGS1 3585/4885
US-20120116128-A1 Process For The Manufacture Of Halogenated Precursors Of Alkenones In The Presence Of A Solvent ALK, HSD17B12, HSD17B10 PTGS1 4222/4885
US-20140051892-A1 Process for chemical synthesis from an alkenone made from a halogenated precursor ALK, CYP4A11, SQLE PTGS1 1439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.