SCHEMBL95007

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19334523	0.86	PGR (0.77)	PGRHSPD1PTPN2PTPN1PTPN5
	SCHEMBL29118877	0.85	PGR (0.67)	PGRHSPD1PTPN2PTPN1PTPN5
	SCHEMBL5040166	0.84	PGR (0.65)	PGRHSPD1PTPN2PTPN1PTPN5
	SCHEMBL4884368	0.82	TDP1 (0.65)	PGRHSPD1PTPN2PTPN1PTPN5
	SCHEMBL96241	0.81	KDM1A (0.64)	HSPD1PTPN2PTPN1PTPN5HSPE1
	SCHEMBL28504340	0.78	HTR6 (0.66)	PGRHSPD1PTPN2PTPN1PTPN5
	SCHEMBL12334075	0.78	NR1H3 (0.66)	PGRHSPD1PTPN2PTPN1PTPN5
	SCHEMBL5037222	0.77	PGR (0.57)	PGRHSPD1PTPN2PTPN1PTPN5
	SCHEMBL11028156	0.77	PGR (0.64)	PGRBRD4BRD1BRPF1ACLY
	SCHEMBL97999	0.77	PGR (0.73)	PGRPTPN2PTPN1PTPN5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.