SCHEMBL950070

SCHEMBL950070

O=c1oc(-c2cc(Br)nn2-c2ncccc2Cl)nc2c(Br)cc(F)cc12

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 3/20 0.38
▸ F2 P00734 1/20 0.31
▸ F10 P00742 1/20 0.31
▸ F7 P08709 1/20 0.31
▸ F3 P13726 1/20 0.31
▸ APEX1 P27695 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL950948 0.90 DHODH (0.39) DHODH
SCHEMBL950141 0.90 DHODH (0.39) DHODH
SCHEMBL950558 0.89 DHODH (0.41) DHODH
SCHEMBL25227368 0.88 DHODH (0.42) DHODHF7F3
SCHEMBL950217 0.87 DHODH (0.41) DHODHF2F10F7F3
SCHEMBL536079 0.87 DHODH (0.39) DHODH
SCHEMBL28525374 0.85 DHODH (0.38) DHODH
SCHEMBL950250 0.85 DHODH (0.40) DHODH
SCHEMBL30749778 0.85 DHODH (0.40) DHODH
SCHEMBL3328151 0.85 DHODH (0.40) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10039284-B2 Pesticidal compositions ISHIHARA SANGYO KAISHA, LTD. (JP) 2018-08-07 — — US disclosed
US-20170280719-A1 PESTICIDAL COMPOSITIONS ISHIHARA SANGYO KAISHA, LTD. (JP) 2017-10-05 — — US disclosed
US-9737074-B2 Pesticidal compositions ISHIHARA SANGYO KAISHA, LTD. (JP) 2017-08-22 — — US disclosed
US-20140194390-A1 PESTICIDAL COMPOSITIONS ISHIHARA SANGYO KAISHA, LTD. (JP) 2014-07-10 — — US disclosed
US-8729106-B2 Pesticidal compositions ISHIHARA SANGYO KAISHA, LTD. (JP) 2014-05-20 — — US disclosed
US-7968573-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-28 — — US disclosed
EP-1937664-B1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2011-06-15 — — EP disclosed
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME IKEGAMI HIROSHI 2011-03-24 — — US disclosed
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 — — US disclosed
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 — — EP disclosed
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 — — EP disclosed
US-20100028304-A1 PESTICIDAL COMPOSITIONS ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-02-04 — — US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 — — US disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 — — WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140194390-A1 PESTICIDAL COMPOSITIONS CNPY2, CNPY3, CRYAA DHODH 3415/4885F2 1727/4885F10 1484/4885
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME ACHE, H1-2, H1-0 DHODH 771/4885F2 1068/4885F10 2564/4885
US-10039284-B2 Pesticidal compositions CNPY2, CNPY3, CRYAA DHODH 3415/4885F2 1727/4885F10 1484/4885
US-20170280719-A1 PESTICIDAL COMPOSITIONS CNPY2, CNPY3, CRYAA DHODH 3415/4885F2 1727/4885F10 1484/4885
US-20100028304-A1 PESTICIDAL COMPOSITIONS CNPY3, CNPY2, CRYAA DHODH 3754/4885F2 2011/4885F10 1380/4885
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT DHODH 284/4885F2 3007/4885F10 3713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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