Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 13/20 | 1.00 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10590162 | 0.91 | FDPS (0.83) | FDPSCA12CA1CA2MMP1 | |
| SCHEMBL9499871 | 0.91 | FDPS (1.00) | FDPSGGPS1SIGMAR1S1PR2S1PR4 | |
| SCHEMBL9394777 | 0.89 | FDPS (1.00) | FDPSGGPS1SIGMAR1S1PR2S1PR4 | |
| SCHEMBL9499493 | 0.81 | FDPS (0.82) | FDPSGGPS1SIGMAR1S1PR2S1PR4 | |
| SCHEMBL12821711 | 0.78 | FDPS (0.72) | FDPSGGPS1 | |
| SCHEMBL12822039 | 0.77 | FDPS (0.70) | FDPSGGPS1S1PR2S1PR4S1PR1 | |
| SCHEMBL4478781 | 0.76 | FDPS (0.61) | FDPSDRD2DRD4OPRM1DRD3 | |
| SCHEMBL9151249 | 0.76 | FDPS (1.00) | FDPSDRD2DRD4DRD3 | |
| SCHEMBL9499526 | 0.75 | FDPS (0.71) | FDPS | |
| SCHEMBL283735 | 0.74 | SIGMAR1 (0.81) | CA12CA1CA2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110807-A | Calcium metabolism disorders | CIBA-GEIGY CORPORATION (US) | 1992-05-05 | — | — | US | claimed |
| EP-0320455-A1 | Araliphatyl aminoalcane diphosphonic acids | CIBA-GEIGY AG (CH) | 1989-06-14 | — | — | EP | claimed |
| EP-0320455-B1 | ARALIPHATYL AMINOALCANE DIPHOSPHONIC ACIDS | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |
| US-5190930-A | Calcium metabolism disorder | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| US-5110807-A | Calcium metabolism disorders | CIBA-GEIGY CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0320455-A1 | Araliphatyl aminoalcane diphosphonic acids | CIBA-GEIGY AG (CH) | 1989-06-14 | — | — | EP | disclosed |