Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500870 | 0.84 | GPR35 (0.68) | GPR35TDP1ALDH1A1CRHBPCRHR2 | |
| SCHEMBL70533 | 0.80 | GPR35 (0.75) | GPR35TDP1TSHRALDH1A1HPGD | |
| SCHEMBL2224314 | 0.77 | GPR35 (0.59) | GPR35TDP1TSHRALDH1A1CRHBP | |
| SCHEMBL30785537 | 0.77 | GPR35 (0.59) | GPR35TDP1TSHRALDH1A1CRHBP | |
| SCHEMBL29516730 | 0.76 | GPR35 (1.00) | GPR35TDP1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL16979 | 0.76 | GPR35 (1.00) | GPR35TDP1TSHRALDH1A1SMN1; SMN2 | |
| Trinitrophenol SCHEMBL10727440 | 0.75 | GPR35 (0.74) | GPR35TDP1TSHRALDH1A1CRHBP | |
| SCHEMBL29457573 | 0.75 | GPR35 (0.57) | GPR35TDP1ALDH1A1TTRKDM4E | |
| SCHEMBL28728496 | 0.75 | GPR35 (0.57) | GPR35TDP1ALDH1A1TTRKDM4E | |
| SCHEMBL9499320 | 0.75 | GPR35 (0.62) | GPR35TDP1TSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312931-B1 | PROCESS FOR THE PREPARATION OF AMINO-1,3 BENZENEDIOL | THE DOW CHEMICAL COMPANY (US) | 1993-04-21 | — | — | EP | claimed |