Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217450 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4ENPSR1GAA | |
| SCHEMBL9218454 | 0.89 | MAPT (0.40) | ALDH1A1MAPTKDM4ENPSR1GAA | |
| SCHEMBL9501521 | 0.89 | MAPT (0.40) | ALDH1A1MAPTKDM4ENPSR1GAA | |
| SCHEMBL9500764 | 0.79 | GAA (0.38) | ALDH1A1MAPTKDM4EGAANPC1 | |
| SCHEMBL9215872 | 0.79 | GAA (0.38) | ALDH1A1MAPTKDM4EGAANPC1 | |
| SCHEMBL9218040 | 0.79 | GAA (0.46) | ALDH1A1MAPTKDM4EGAANPC1 | |
| SCHEMBL9501932 | 0.79 | GAA (0.46) | ALDH1A1MAPTKDM4EGAANPC1 | |
| SCHEMBL9216153 | 0.77 | GAA (0.42) | ALDH1A1MAPTKDM4EGAANPC1 | |
| SCHEMBL9501648 | 0.77 | GAA (0.42) | ALDH1A1MAPTKDM4EGAANPC1 | |
| SCHEMBL9216623 | 0.75 | GAA (0.38) | ALDH1A1MAPTGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189053-A | Insecticide, acaricide and endoparasiticide | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-02-23 | — | — | US | disclosed |
| US-5109012-A | 2-IMIDAZOL(IN)E SUBSTITUTED ARYL-1,2,3-TRIAZOLE PESTICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |