Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508110 | 0.90 | THRB (0.38) | TSHRCA1CA2 | |
| SCHEMBL9498867 | 0.90 | ADRB2 (0.38) | CYP3A4ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL14779051 | 0.87 | ADRB2 (0.36) | CYP3A4ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL14778845 | 0.85 | TSHR (0.38) | ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL14778504 | 0.85 | TSHR (0.38) | ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL14779155 | 0.85 | TSHR (0.38) | ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL14778437 | 0.85 | TSHR (0.38) | ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL14779834 | 0.85 | TSHR (0.38) | ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL9501369 | 0.83 | TSHR (0.32) | TSHR | |
| SCHEMBL4980904 | 0.81 | TSHR (0.42) | CYP3A4ADRB2ADRB1ADRB3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072648-A1 | SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-21 | — | — | US | disclosed |
| EP-0272110-B1 | ERYTHROMYCIN A DERIVATIVES AND METHOD FOR THE PREPARATION OF THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-4990602-A | Bactericides | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0272110-A2 | Erythromycin a derivatives and method for the preparation of the same | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1988-06-22 | — | — | EP | disclosed |