Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA6 | P23280 | 4/20 | 0.46 |
| ▸ | CA7 | P43166 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24711870 | 0.91 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL24727915 | 0.89 | CA2 (0.46) | CA12CA6CA7CA9CA14 | |
| SCHEMBL30062272 | 0.88 | KDM4E (0.52) | MEN1KMT2ARECQLKDM4ECA2 | |
| SCHEMBL31555925 | 0.88 | KDM4E (0.52) | MEN1KMT2ARECQLKDM4ECA2 | |
| SCHEMBL1507545 | 0.88 | KDM4E (0.52) | MEN1KMT2ARECQLKDM4ECA2 | |
| SCHEMBL3570047 | 0.88 | KDM4E (0.52) | MEN1KMT2ARECQLKDM4ECA2 | |
| SCHEMBL6686436 | 0.88 | KDM4E (0.52) | MEN1KMT2ARECQLKDM4ECA2 | |
| SCHEMBL18593493 | 0.86 | KDM4E (0.49) | CA12CA6CA7CA9CA14 | |
| SCHEMBL44670 | 0.85 | KDM4E (0.55) | MEN1KMT2ARECQLKDM4ECA2 | |
| SCHEMBL4397414 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320960-B1 | AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-05-12 | — | — | EP | disclosed |
| US-5145848-A | AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1992-09-08 | — | — | US | disclosed |
| EP-0396588-A1 | AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1990-11-14 | — | — | EP | disclosed |
| WO-1989005815-A1 | AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-06-29 | — | — | WO | disclosed |
| EP-0320960-A1 | Amino anthracenediones-bis platinum complexes, useful as antitumoral agents | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1989-06-21 | — | — | EP | disclosed |