SCHEMBL6686436

SCHEMBL6686436

COCCOCCOCCNCCOCCOCCOC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.52
RECQL P46063 1/20 0.52
ALDH1A1 P00352 6/20 0.40
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
NPC1 O15118 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
TSHR P16473 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
CA2 P00918 1/20 0.35
RAD52 P43351 1/20 0.35
PAX8 Q06710 1/20 0.35
ADRB2 P07550 1/20 0.33
LMNA P02545 1/20 0.33
PKM P14618 1/20 0.32
ABCB11 O95342 1/20 0.31
CYP3A4 P08684 1/20 0.31
ADRA2B P18089 1/20 0.31
OPRD1 P41143 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31555925 1.00 KDM4E (0.52) KDM4ERECQLALDH1A1MEN1KMT2A
SCHEMBL3570047 1.00 KDM4E (0.52) KDM4ERECQLALDH1A1MEN1KMT2A
SCHEMBL30062272 1.00 KDM4E (0.52) KDM4ERECQLALDH1A1MEN1KMT2A
SCHEMBL1507545 1.00 KDM4E (0.52) KDM4ERECQLALDH1A1MEN1KMT2A
SCHEMBL44670 0.97 KDM4E (0.55) KDM4ERECQLALDH1A1MEN1KMT2A
SCHEMBL18879745 0.94 KDM4E (0.57) KDM4ERECQLALDH1A1MEN1KMT2A
SCHEMBL1133540 0.94 KDM4E (0.52) KDM4ERECQLALDH1A1MEN1KMT2A
SCHEMBL24508502 0.90 KDM4E (0.50) KDM4ERECQLALDH1A1MEN1KMT2A
SCHEMBL17992469 0.90 KDM4E (0.50) KDM4ERECQLALDH1A1MEN1KMT2A
SCHEMBL19478680 0.90 KDM4E (0.50) KDM4ERECQLALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0018884-B1 PROCESS FOR THE PREPARATION OF TRIS(ETHER AMINES) AND SO OBTAINED TRIS(ETHER AMINES) RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1981-11-04 EP claimed
EP-4702004-A1 NONIONIC SURFACTANTS Detect, Inc. (US) 2026-03-04 EP disclosed
US-20250313572-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE ABBVIE INC (US) 2025-10-09 US disclosed
US-20250177533-A1 PHOTODYNAMIC THERAPY AND DIAGNOSIS Invion Limited (AU) 2025-06-05 US disclosed
US-20240360076-A1 NONIONIC SURFACTANTS DETECT INC (US) 2024-10-31 US disclosed
EP-4436971-A1 PHOTODYNAMIC THERAPY AND DIAGNOSIS RMW Cho Group Limited (HK) 2024-10-02 EP disclosed
US-20240228509-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE ABBVIE INC (US) 2024-07-11 US disclosed
CN-118001423-A Hydrophilic anti-Nectin-4 antibody coupled drug as well as preparation method and application thereof 杭州爱科瑞思生物医药有限公司 2024-05-10 CN disclosed
US-20230399340-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE ABBVIE INC (US) 2023-12-14 US disclosed
WO-2023094677-A1 PHOTODYNAMIC THERAPY AND DIAGNOSIS RMW CHO GROUP LIMITED (CN) 2023-06-01 WO disclosed
US-6348200-B1 OXYALKYLAMIDE OR AMINE DERIVATIVES;AT LEAST ONE OF POLYHYDRIC ALCOHOLS, OR VEGETABLE EXTRACTS, OR ORGANIC ACIDS; IMPROVES WATER-RETAINING ABILITY OF HORNY LAYER, CURES ROUGHNESS AND PREVENTS WRINKLES KAO CORPORATION (JP) 2002-02-19 US disclosed
US-6187955-B1 A MOISTURIZER FOR SOFTENING SKINS; USEFUL AS COMPONENTS OF COSMETIC FORMULATIONS KAO CORPORATION (JP) 2001-02-13 US disclosed
US-5919432-A Polyaminated ligands and metal complexes thereof GUERBET S.A. (FR) 1999-07-06 US disclosed
EP-0914333-A1 PEPTIDE DERIVATIVES ZENECA LIMITED (GB) 1999-05-12 EP disclosed
US-5723133-A GUANIDINE WITH ORGANIC ACID FOR SKIN SOFTENING KAO CORPORATION (JP) 1998-03-03 US disclosed
US-5712389-A Polyaminated ligands and metal complexes thereof GUERBET S.A. (FR) 1998-01-27 US disclosed
WO-1997046578-A1 PEPTIDE DERIVATIVES ZENECA LIMITED (GB) 1997-12-11 WO disclosed
EP-0805674-A1 SKIN AND HAIR COSMETIC COMPOSITIONS Kao Corporation (JP) 1997-11-12 EP disclosed
WO-1997014401-A1 SKIN AND HAIR COSMETIC COMPOSITIONS KAO CORPORATION (JP) 1997-04-24 WO disclosed
US-4504682-A Novel polyoxaalkyl aminoalcohols RHONE-POULENC INDUSTRIES (FR) 1985-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228509-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE MCL1, BCL2A1, BCL2L10 KDM4E 1725/4885RECQL 83/4885ALDH1A1 641/4885
US-20240360076-A1 NONIONIC SURFACTANTS POLL, POLRMT, POLI KDM4E 4782/4885RECQL 991/4885ALDH1A1 4251/4885
US-20250177533-A1 PHOTODYNAMIC THERAPY AND DIAGNOSIS PPOX, PPIF, ALAD KDM4E 4440/4885RECQL 1504/4885ALDH1A1 618/4885
US-20250313572-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE MCL1, BCL2A1, BCL2L10 KDM4E 1725/4885RECQL 83/4885ALDH1A1 641/4885
US-20230399340-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE MCL1, BCL2A1, BCL2L10 KDM4E 1725/4885RECQL 83/4885ALDH1A1 641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.