Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8745489 | 0.83 | MAPT (0.48) | S100BMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL3408798 | 0.83 | S100B (0.52) | S100BMAPTKMT2AMEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL2140481 | 0.83 | S100B (0.64) | S100BMAPTKMT2AMEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL10945925 | 0.83 | S100B (0.64) | S100BMAPTKMT2AMEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL10371487 | 0.83 | S100B (0.64) | S100BMAPTKMT2AMEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL9566805 | 0.83 | S100B (0.64) | S100BMAPTKMT2AMEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL10582678 | 0.83 | S100B (0.64) | S100BMAPTKMT2AMEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL5151353 | 0.82 | S100B (0.62) | S100BMAPTKMT2AMEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL10686415 | 0.82 | S100B (0.62) | S100BMAPTKMT2AMEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL8415500 | 0.80 | S100B (0.47) | S100BMAPTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536387-A1 | 3-ANILINO PYRAZOLONE MAGENTA COUPLERS AND PROCESS | EASTMAN KODAK COMPANY (US) | 1993-04-14 | — | — | EP | disclosed |
| WO-1992018902-A1 | 3-ANILINO PYRAZOLONE MAGENTA COUPLERS AND PROCESS | EASTMAN KODAK COMPANY (US) | 1992-10-29 | — | — | WO | disclosed |