Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 9/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502058 | 0.88 | ADRB2 (0.48) | ADRB2GSK3BHTTALDH1A1LMNA | |
| SCHEMBL1345409 | 0.83 | ADRB2 (0.43) | ADRB2GSK3BHTTALDH1A1LMNA | |
| SCHEMBL9501129 | 0.81 | ADRB2 (0.51) | ADRB2GSK3BHTTKMT2ASTAT3 | |
| SCHEMBL5507636 | 0.80 | ADRB2 (0.50) | ADRB2GSK3BHTTKMT2ASTAT3 | |
| SCHEMBL30181222 | 0.80 | ADRB2 (0.50) | ADRB2GSK3BHTTKMT2ASTAT3 | |
| SCHEMBL9501167 | 0.77 | ADRB2 (0.43) | ADRB2GSK3BHTTALDH1A1LMNA | |
| SCHEMBL9501304 | 0.77 | GSK3B (0.49) | ADRB2GSK3BHTTKMT2ASTAT3 | |
| SCHEMBL263981 | 0.77 | STAT3 (0.48) | ADRB2GSK3BHTTKMT2ASTAT3 | |
| SCHEMBL9501093 | 0.77 | GSK3B (0.54) | GSK3BKCNH2HRH3 | |
| SCHEMBL1345135 | 0.75 | GSK3B (0.50) | ADRB2GSK3BHTTSTAT3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312085-B1 | NOVEL QUINOLINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND ANTIBACTERIAL AGENT CONTAINING THEM | Dainippon Pharmaceutical Co., Ltd. (JP) | 1993-05-12 | — | — | EP | disclosed |
| US-5164392-A | Active against streptococci and staphylococci | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| US-5013841-A | Oxo quinoline derivatives | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1991-05-07 | — | — | US | disclosed |
| EP-0312085-A2 | Novel quinoline derivatives, processes for preparation thereof and antibacterial agent containing them | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-04-19 | — | — | EP | disclosed |