SCHEMBL9501212

SCHEMBL9501212

CCc1ccccc1NC(Nc1ccccc1CC)Nc1ccccc1CC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
GAA P10253 3/20 0.47
MAPT P10636 2/20 0.47
TAS1R3 Q7RTX0 1/20 0.46
TAS1R1 Q7RTX1 1/20 0.46
POLB P06746 4/20 0.44
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8097565 0.84 ALDH1A1 (0.46) ALDH1A1GAAMAPTTAS1R3TAS1R1
SCHEMBL19038256 0.84 ALDH1A1 (0.46) ALDH1A1GAAMAPTTAS1R3TAS1R1
SCHEMBL30316736 0.84 ALDH1A1 (0.46) ALDH1A1GAAMAPTTAS1R3TAS1R1
SCHEMBL6023261 0.81 ALDH1A1 (0.47) ALDH1A1GAAMAPTTAS1R3TAS1R1
SCHEMBL22705622 0.79 ALDH1A1 (0.46) ALDH1A1GAAMAPTTAS1R3TAS1R1
SCHEMBL28933312 0.79 MEN1 (0.45) ALDH1A1GAAMAPTTAS1R3TAS1R1
SCHEMBL9281088 0.78 GAA (0.53) ALDH1A1GAAMAPTTAS1R3TAS1R1
SCHEMBL1548694 0.78 ALDH1A1 (0.54) ALDH1A1GAAMAPTPOLBGRIN2D
SCHEMBL24315973 0.78 ALDH1A1 (0.42) ALDH1A1GAAMAPTTAS1R3TAS1R1
SCHEMBL10409255 0.78 ALDH1A1 (0.42) ALDH1A1GAAMAPTTAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0317508-B1 AMINIC ORTHOESTER STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1993-06-23 EP claimed
EP-0317508-A2 Aminic orthoester stabilized compositions CIBA-GEIGY AG (CH) 1989-05-24 EP claimed
EP-0317508-B1 AMINIC ORTHOESTER STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1993-06-23 EP disclosed
US-4939300-A Polymer stabilizer; oxidation, heat, and actinic radiation resistance CIBA-GEIGY CORPORATION (US) 1990-07-03 US disclosed
EP-0317508-A2 Aminic orthoester stabilized compositions CIBA-GEIGY AG (CH) 1989-05-24 EP disclosed