Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500400 | 0.89 | ACE (0.52) | — | |
| SCHEMBL6285952 | 0.88 | PREP (0.65) | PREP | |
| SCHEMBL6285958 | 0.88 | PREP (0.65) | PREP | |
| SCHEMBL10339417 | 0.86 | PREP (0.65) | PREP | |
| SCHEMBL9501238 | 0.86 | FKBP1A (0.54) | FFAR1 | |
| SCHEMBL31324093 | 0.78 | DPP4 (0.58) | HTR1AHTR7 | |
| SCHEMBL9501712 | 0.77 | PREP (0.48) | PREP | |
| SCHEMBL8153242 | 0.76 | MEN1 (0.55) | PREP | |
| SCHEMBL8153245 | 0.76 | MEN1 (0.55) | PREP | |
| SCHEMBL7330019 | 0.76 | MEN1 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232849-B1 | PYRROLIDINEAMIDE DERIVATIVE OF ACYLAMINO ACID, PHARMACEUTICAL COMPOSITION AND USE | SUNTORY LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |
| US-5198458-A | Pyrrolidineamide derivatives of acylamino acid and pharmaceutical composition containing the same | SUNTORY LIMITED (JP) | 1993-03-30 | — | — | US | disclosed |
| US-4826870-A | CURING AMNESIA | SUNTORY LIMITED (JP) | 1989-05-02 | — | — | US | disclosed |
| EP-0232849-A2 | Pyrrolidineamide derivative of acylamino acid, pharmaceutical composition and use | SUNTORY LIMITED (JP) | 1987-08-19 | — | — | EP | disclosed |