Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657838 | 0.77 | MAPT (0.40) | MAPTLMNAGAAKDM4EALDH1A1 | |
| SCHEMBL11639932 | 0.75 | PKM (0.47) | MAPTLMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30671626 | 0.72 | MAPT (0.39) | MAPTLMNAGAAKDM4EALDH1A1 | |
| SCHEMBL657497 | 0.72 | MAPT (0.39) | MAPTLMNAGAAKDM4EALDH1A1 | |
| SCHEMBL1429528 | 0.69 | MAPT (0.47) | MAPTLMNAGAAKDM4EALDH1A1 | |
| SCHEMBL4002381 | 0.67 | CASP1 (0.47) | MAPTLMNAGAAKDM4EALDH1A1 | |
| SCHEMBL4476431 | 0.67 | MAOB (0.50) | MAPTLMNAGAAKDM4EALDH1A1 | |
| SCHEMBL2060404 | 0.67 | FABP6 (0.67) | MAPTLMNAGAAPDE3BPDE3A | |
| SCHEMBL29384774 | 0.67 | FABP6 (0.67) | MAPTLMNAGAAPDE3BPDE3A | |
| SCHEMBL6205990 | 0.64 | CASP1 (0.44) | MAPTLMNAGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355598-B1 | BETA-PHENOXYETHYL AMINES AND THEIR USE IN THE PREPARATION OF DYES | BAYER AG (DE) | 1993-06-16 | — | — | EP | claimed |
| EP-0355598-A2 | Beta-phenoxyethyl amines and their use in the preparation of dyes | BAYER AG (DE) | 1990-02-28 | — | — | EP | claimed |
| EP-0355598-B1 | BETA-PHENOXYETHYL AMINES AND THEIR USE IN THE PREPARATION OF DYES | BAYER AG (DE) | 1993-06-16 | — | — | EP | disclosed |
| US-5126481-A | Cyclization, reduction, decyclization | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |
| US-5041629-A | Beta-phenoxyethylamines and their use for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-20 | — | — | US | disclosed |
| EP-0355598-A2 | Beta-phenoxyethyl amines and their use in the preparation of dyes | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |