SCHEMBL18458595

SCHEMBL18458595

CC1CCC(c2ccc(-c3ccc(C4CCCCC4)cc3F)cc2)CC1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.56
APP P05067 3/20 0.56
CYP2C9 P11712 2/20 0.56
FASN P49327 1/20 0.46
ESR2 Q92731 1/20 0.44
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
HSP90AA1 P07900 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
PDK2 Q15119 1/20 0.37
S1PR1 P21453 4/20 0.37
S1PR5 Q9H228 2/20 0.37
S1PR4 O95977 1/20 0.37
NOTUM Q6P988 1/20 0.36
DHODH Q02127 1/20 0.36
FFAR4 Q5NUL3 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14211884 1.00 CYP3A4 (0.56) CYP3A4APPCYP2C9FASNESR2
SCHEMBL10091195 1.00 CYP3A4 (0.56) CYP3A4APPCYP2C9FASNESR2
SCHEMBL12377041 0.94 FASN (0.49) CYP3A4APPCYP2C9FASNESR2
SCHEMBL9501457 0.91 CYP3A4 (0.60) CYP3A4APPCYP2C9CYP2D6CYP2C19
SCHEMBL16317705 0.88 FASN (0.47) CYP3A4APPCYP2C9FASNESR2
SCHEMBL20090795 0.87 FASN (0.45) CYP3A4APPCYP2C9FASNESR2
SCHEMBL91987 0.87 FASN (0.47) CYP3A4APPCYP2C9FASNESR2
SCHEMBL2741531 0.87 FASN (0.47) CYP3A4APPCYP2C9FASNESR2
SCHEMBL19820860 0.86 FASN (0.47) CYP3A4APPCYP2C9FASNESR2
SCHEMBL18807493 0.85 CYP3A4 (0.53) CYP3A4APPCYP2C9FASNCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-11345857-B2 Spontaneous alignment assistant for liquid crystal compositions DIC CORPORATION (JP) 2022-05-31 US disclosed
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 US disclosed
US-11312906-B2 Polymerizable monomer, liquid crystal composition using polymerizable monomer, and liquid crystal display device DIC CORPORATION (JP) 2022-04-26 US disclosed
US-11162028-B2 Liquid crystal composition and application thereof JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-11-02 US disclosed
US-20210223635-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2021-07-22 US disclosed
US-20210171831-A1 ALIGNMENT AID, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2021-06-10 US disclosed
US-20210071084-A1 SPONTANEOUS ALIGNMENT ASSISTANT FOR LIQUID CRYSTAL COMPOSITIONS DIC CORPORATION (JP) 2021-03-11 US disclosed
US-10927300-B2 Spontaneous alignment assistant for liquid crystal compositions DIC CORPORATION (JP) 2021-02-23 US disclosed
US-20170226420-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2017-08-10 US disclosed
US-20170218271-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2017-08-03 US disclosed
US-20170210986-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2017-07-27 US disclosed
US-20170210989-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-07-27 US disclosed
US-9701905-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2017-07-11 US disclosed
US-9688913-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-06-27 US disclosed
US-9650572-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-05-16 US disclosed
US-9637684-B2 Composition and liquid crystal display element using same DIC CORPORATION (JP) 2017-05-02 US disclosed
US-9580654-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-02-28 US disclosed
US-20170029700-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11345857-B2 Spontaneous alignment assistant for liquid crystal compositions VAC14, VAPA, SFN CYP3A4 4304/4885APP 1080/4885CYP2C9 4553/4885
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 CYP3A4 3290/4885APP 1137/4885CYP2C9 3955/4885
US-20210071084-A1 SPONTANEOUS ALIGNMENT ASSISTANT FOR LIQUID CRYSTAL COMPOSITIONS VAC14, VAPA, SFN CYP3A4 4304/4885APP 1080/4885CYP2C9 4553/4885
US-10927300-B2 Spontaneous alignment assistant for liquid crystal compositions KTN1, KCNA1, KNTC1 CYP3A4 3865/4885APP 2148/4885CYP2C9 4406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.