Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetoacetic Acid SCHEMBL10586878 | 0.91 | MAPT (0.48) | TSHRRECQLMAPTKDM4EHIF1A | |
| Aniline SCHEMBL27979926 | 0.86 | TSHR (0.58) | TSHRMAPTALDH1A1KDM4EHIF1A | |
| 4-Aminophenol SCHEMBL11500221 | 0.83 | CYP3A4 (0.52) | TSHRMAPTALDH1A1KDM4EHIF1A | |
| Acetoacetic Acid SCHEMBL11500325 | 0.83 | ACHE (0.52) | TSHRMAPTALDH1A1KDM4EHIF1A | |
| Aniline SCHEMBL27866527 | 0.82 | TSHR (0.52) | TSHRMAPTALDH1A1KDM4EHIF1A | |
| Biphenyl SCHEMBL27519918 | 0.82 | SMN1; SMN2 (0.52) | TSHRRECQLMAPTALDH1A1KDM4E | |
| Biphenyl SCHEMBL8077261 | 0.82 | SMN1; SMN2 (0.52) | TSHRRECQLMAPTALDH1A1KDM4E | |
| 4-Chloroaniline SCHEMBL11070783 | 0.82 | MEN1 (0.46) | TSHRMAPTALDH1A1KDM4EHIF1A | |
| Aminobenzoic Acid SCHEMBL11235310 | 0.82 | MAPT (0.50) | TSHRMAPTALDH1A1KDM4EHIF1A | |
| Aniline SCHEMBL11191296 | 0.81 | TSHR (0.58) | TSHRRECQLMAPTKDM4EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344343-B1 | PROCESS FOR THE REGIOSPECIFIC SULFONATION OF 2-AMINO-NAPHTALENES SUBSTITUTED IN THE 5- OR 7-POSITION BY A FIBRE REACTIVE VS-GROUP, THE NOVEL 5-SULFO-SUBSTITUTED FIBER-REACTIVE 2-AMINO-NAPHTHALENE, AND FIBRE-REACTIVE AZO DYES THEREOF | HOECHST CELANESE CORPORATION (US) | 1993-04-21 | — | — | EP | claimed |
| EP-0344343-A1 | Process for the regiospecific sulfonation of 2-amino-naphtalenes substituted in the 5- or 7-position by a fibre reactive vs-group, the novel 5-sulfo-substituted fiber-reactive 2-amino-naphthalene, and fibre-reactive azo dyes thereof | HOECHST CELANESE CORPORATION (US) | 1989-12-06 | — | — | EP | claimed |