Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | PRNP | P04156 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.44 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.43 |
| ▸ | MIF | P14174 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475131 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2PRNPKDM4EGLAMEN1 | |
| SCHEMBL630002 | 0.77 | SMN1; SMN2 (0.66) | SMN1; SMN2PRNPCYP26A1CA1CA2 | |
| SCHEMBL28277512 | 0.75 | SIGMAR1 (0.46) | MAPTTDP1L3MBTL1 | |
| SCHEMBL13477053 | 0.75 | SMN1; SMN2 (0.70) | SMN1; SMN2PRNPKDM4EGLAMEN1 | |
| SCHEMBL13477088 | 0.75 | SMN1; SMN2 (0.70) | SMN1; SMN2PRNPKDM4EGLACYP26A1 | |
| SCHEMBL7832178 | 0.74 | SMN1; SMN2 (0.59) | SMN1; SMN2PRNPKDM4EGLAMEN1 | |
| SCHEMBL27081326 | 0.74 | SMN1; SMN2 (0.59) | SMN1; SMN2PRNPCA1CA2CA4 | |
| SCHEMBL18815844 | 0.74 | SMN1; SMN2 (0.59) | SMN1; SMN2PRNPCA1CA2CA4 | |
| SCHEMBL13822557 | 0.74 | SMN1; SMN2 (0.55) | SMN1; SMN2PRNPKDM4EMEN1KMT2A | |
| SCHEMBL8012040 | 0.73 | SMN1; SMN2 (0.61) | SMN1; SMN2PRNPCYP26A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279466-B1 | NOVEL NAPHTHALENE DERIVATIVES AND ANTIALLERGY AND ANTI-INFLAMMATORY PHARMACEUTICALS | WARNER-LAMBERT COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| US-4767776-A | N-1H-tetrazol-5-yl-2-naphthalene carboxamides and their use as antiallergy and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0279466-A2 | Novel naphthalene derivatives and antiallergy and anti-inflammatory pharmaceuticals | WARNER-LAMBERT COMPANY (US) | 1988-08-24 | — | — | EP | disclosed |