Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.52 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11844117 | 0.82 | HSP90AA1 (0.48) | SMN1; SMN2DGAT1KDM4EMTNR1AMTNR1B | |
| SCHEMBL11845491 | 0.79 | DGAT1 (0.46) | DGAT1KDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL14061713 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2DGAT1PRNPMTNR1AMTNR1B | |
| SCHEMBL2421113 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2DGAT1PRNPKDM4EGLA | |
| SCHEMBL7302991 | 0.78 | DGAT1 (0.56) | SMN1; SMN2DGAT1MTNR1AMTNR1BMETAP1 | |
| SCHEMBL30475131 | 0.76 | SMN1; SMN2 (0.67) | SMN1; SMN2PRNPKDM4EGLACYP26A1 | |
| SCHEMBL630002 | 0.76 | SMN1; SMN2 (0.66) | SMN1; SMN2PRNPCYP26A1ALDH1A1METAP1 | |
| SCHEMBL27582482 | 0.76 | DGAT1 (0.48) | SMN1; SMN2DGAT1METAP1MEN1KMT2A | |
| SCHEMBL9501532 | 0.74 | SMN1; SMN2 (0.61) | SMN1; SMN2DGAT1PRNPKDM4EGLA | |
| SCHEMBL4621041 | 0.73 | SMN1; SMN2 (0.62) | SMN1; SMN2DGAT1PRNPKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |