Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 4/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.45 |
| ▸ | GABRP | O00591 | 3/20 | 0.45 |
| ▸ | GABRD | O14764 | 3/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.45 |
| ▸ | GABRE | P78334 | 3/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219979 | 1.00 | GABRB3 (0.46) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9218195 | 0.82 | GABRA2 (0.46) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9501917 | 0.82 | GABRA2 (0.46) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9704816 | 0.80 | GAA (0.48) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9704820 | 0.80 | GAA (0.48) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9218454 | 0.79 | MAPT (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9703353 | 0.79 | GAA (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9703357 | 0.79 | GAA (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9501521 | 0.79 | MAPT (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9703551 | 0.78 | GAA (0.37) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189053-A | Insecticide, acaricide and endoparasiticide | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-02-23 | — | — | US | disclosed |
| US-5109012-A | 2-IMIDAZOL(IN)E SUBSTITUTED ARYL-1,2,3-TRIAZOLE PESTICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |