Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.54 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.54 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22384790 | 0.87 | LTA4H (0.44) | CHRNA7CHRNA10CHRNA9PPARALTA4H | |
| SCHEMBL8047466 | 0.86 | LTA4H (0.51) | CHRNA7LTA4HCYP2D6CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL10620816 | 0.84 | LTA4H (0.50) | CHRNA7LTA4HCYP2D6CYP1A2CYP2C9 | |
| SCHEMBL11674918 | 0.83 | LTA4H (0.49) | LTA4HCYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10529326 | 0.83 | TSHR (0.55) | LTA4HCYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11677403 | 0.83 | LSS (0.57) | CHRNA7LTA4HCYP2D6CYP1A2CYP2C9 | |
| SCHEMBL10530995 | 0.83 | LTA4H (0.63) | LTA4HCYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11678365 | 0.82 | KMT2A (0.49) | LTA4HCYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11217525 | 0.82 | TDP1 (0.50) | LTA4HCYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17858645 | 0.82 | ALDH1A1 (0.47) | CHRNA7CHRNA10CHRNA9TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271444-B1 | DISPERSE DYES | CIBA-GEIGY AG (CH) | 1993-04-28 | — | — | EP | disclosed |
| US-5037967-A | Monoazo couplers for disperse dyes | CIBA-GEIGY CORPORATION (US) | 1991-08-06 | — | — | US | disclosed |
| US-4910299-A | Azo group attached to phenyl ring | CIBA-GEIGY CORPORATION (US) | 1990-03-20 | — | — | US | disclosed |
| EP-0271444-A2 | Disperse dyes | CIBA-GEIGY AG (CH) | 1988-06-15 | — | — | EP | disclosed |