SCHEMBL9501660

SCHEMBL9501660

O=C1C=CC(=O)N1C1CCCCC1c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 14/20 0.44
OPRM1 P35372 8/20 0.44
SLC6A5 Q9Y345 8/20 0.44
KCNH2 Q12809 1/20 0.44
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
OPRL1 P41146 4/20 0.42
SCN1A P35498 1/20 0.42
SCN2A Q99250 1/20 0.42
SCN3A Q9NY46 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1028867 0.96 SCN1A (0.45) SLC6A9OPRM1SLC6A5KCNH2OPRL1
SCHEMBL4607546 0.77 SCN1A (0.44) SLC6A9OPRM1SLC6A5KCNH2SCN1A
SCHEMBL4607545 0.77 SCN1A (0.44) SLC6A9OPRM1SLC6A5KCNH2SCN1A
SCHEMBL10714854 0.76 ALDH1A1 (0.36) KMT2AALDH1A1NPSR1
SCHEMBL11904658 0.73 MEN1 (0.65) KCNH2MEN1KMT2AALDH1A1GAA
SCHEMBL415662 0.73 MEN1 (0.65) KCNH2MEN1KMT2AALDH1A1GAA
SCHEMBL8286207 0.72 SLC6A9 (0.54) SLC6A9OPRM1SLC6A5KCNH2OPRL1
SCHEMBL5556935 0.72 SLC6A9 (0.54) SLC6A9OPRM1SLC6A5KCNH2OPRL1
SCHEMBL5556937 0.72 SLC6A9 (0.54) SLC6A9OPRM1SLC6A5KCNH2OPRL1
SCHEMBL5562017 0.72 SLC6A9 (0.54) SLC6A9OPRM1SLC6A5KCNH2OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372213-B1 PROTECTIVE METHYCRYLATE LAYER FOR POLYCARBONATE, CONTAINING A UV ABSORBER RÖHM GMBH (DE) 1993-05-19 EP disclosed
EP-0283975-B1 COMPATIBLE BLENDS OF POLYCARBONATE AND METHYL METHACRYLATE COPOLYMERS RÖHM GMBH (DE) 1993-04-21 EP disclosed
EP-0368094-B1 IMPACT-RESISTANT PROTECTION METHACRYLATE LAYER CONTAINING A UV ABSORBER FOR POLYCARBONATE RÖHM GMBH (DE) 1992-05-06 EP disclosed
US-5063112-A IMPACT-RESISTANT METHACRYLATE PROTECTIVE LAYER FOR POLYCARBONATE, CONTAINING UV ABSORBER ROHM GMBH CHEMISCHE FABRIK (DE) 1991-11-05 US disclosed
US-5061558-A METHACRYLATE PROTECTIVE COATING CONTAINING A UV-ABSORBER FOR POLYCARBONATE ROHM GMBH CHEMISCHE FABRIK (DE) 1991-10-29 US disclosed
US-4950716-A RADIATION TRANSPARENT ROHM GMBH CHEMISCHE FABRIK (DE) 1990-08-21 US disclosed
EP-0372213-A1 Protective methycrylate layer for polycarbonate, containing a UV absorber RÖHM GMBH (DE) 1990-06-13 EP disclosed
EP-0368094-A1 Impact-resistant protection methacrylate layer containing a UV absorber for polycarbonate RÖHM GMBH (DE) 1990-05-16 EP disclosed
EP-0283975-A2 Compatible blends of polycarbonate and methyl methacrylate copolymers RÖHM GMBH (DE) 1988-09-28 EP disclosed