Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132126 | 0.87 | ABL1 (0.49) | ABL1NAAAALDH1A1EGFRALOX5 | |
| SCHEMBL7951728 | 0.85 | ABL1 (0.51) | ABL1NAAAALDH1A1EGFRALOX5 | |
| SCHEMBL9484979 | 0.83 | ABL1 (0.55) | ABL1NAAAALDH1A1EGFRALOX5 | |
| SCHEMBL29578255 | 0.83 | ABL1 (0.55) | ABL1ALDH1A1KCNH3GPR84PRSS1 | |
| SCHEMBL9650900 | 0.81 | ABL1 (0.50) | ABL1NAAAALDH1A1EGFRALOX5 | |
| SCHEMBL11638268 | 0.80 | ABL1 (0.65) | ABL1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29262271 | 0.80 | ABL1 (0.53) | ABL1ALDH1A1HTTKCNH3TDP1 | |
| SCHEMBL19145089 | 0.79 | ARG1 (0.52) | ABL1NAAAALDH1A1ALOX5PTGS2 | |
| SCHEMBL6229918 | 0.79 | ALDH1A1 (0.41) | ALDH1A1EGFRHPGDKDM4EMEN1 | |
| SCHEMBL2446050 | 0.79 | ABL1 (0.68) | ABL1ALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285109-A1 | Process for the preparation of 2-amino-4-acylamino-phenyl ether | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | claimed |
| EP-0165564-B1 | PROCESS FOR THE PREPARATION OF 4-ACYLAMINO-2-ALKYLAMINOPHENYL ETHERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-25 | — | — | EP | claimed |
| EP-0165564-A2 | Process for the preparation of 4-acylamino-2-alkylaminophenyl ethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-27 | — | — | EP | claimed |
| EP-0007738-B1 | PROCESS FOR PRODUCING 2-AMINO-4-ACYLAMINOPHENYL ETHER AND 2,4-DIAMINOPHENYL ETHER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-12-29 | — | — | EP | claimed |
| EP-0328968-B1 | PROCESS FOR THE PREPARATION OF 4-ACYLAMINO-2-AMINO ALKOXY BENZENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | disclosed |
| EP-0285109-B1 | PROCESS FOR THE PREPARATION OF 2-AMINO-4-ACYLAMINO-PHENYL ETHER | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | disclosed |
| EP-0328968-A2 | Process for the preparation of 4-acylamino-2-amino alkoxy benzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | disclosed |
| EP-0285109-A1 | Process for the preparation of 2-amino-4-acylamino-phenyl ether | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | disclosed |
| EP-0165564-B1 | PROCESS FOR THE PREPARATION OF 4-ACYLAMINO-2-ALKYLAMINOPHENYL ETHERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-25 | — | — | EP | disclosed |
| EP-0165564-A2 | Process for the preparation of 4-acylamino-2-alkylaminophenyl ethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-27 | — | — | EP | disclosed |
| EP-0165564-A2 | Process for the preparation of 4-acylamino-2-alkylaminophenyl ethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-27 | — | — | EP | disclosed |
| EP-0007738-B1 | PROCESS FOR PRODUCING 2-AMINO-4-ACYLAMINOPHENYL ETHER AND 2,4-DIAMINOPHENYL ETHER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-12-29 | — | — | EP | disclosed |
| EP-0007738-A1 | Process for producing 2-amino-4-acylaminophenyl ether and 2,4-diaminophenyl ether | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-02-06 | — | — | EP | disclosed |