Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5742878 | 0.87 | CACNA1A (0.62) | ACEALDH1A1SMN1; SMN2 | |
| SCHEMBL5742876 | 0.87 | CACNA1A (0.62) | ACEALDH1A1SMN1; SMN2 | |
| SCHEMBL7013528 | 0.87 | PREP (0.57) | ALDH1A1SMN1; SMN2NPC1HPGDTSHR | |
| SCHEMBL9500411 | 0.87 | ALDH1A1 (0.50) | ACEALDH1A1SMN1; SMN2NPC1HPGD | |
| SCHEMBL5742535 | 0.79 | ACE (0.62) | ACERAB9AREN | |
| SCHEMBL15854285 | 0.79 | ACE (0.62) | ACERAB9AREN | |
| SCHEMBL5742529 | 0.79 | ACE (0.62) | ACERAB9AREN | |
| SCHEMBL10173234 | 0.79 | ACE (0.55) | ACEALDH1A1SMN1; SMN2REN | |
| SCHEMBL9362237 | 0.79 | ACE (0.55) | ACEALDH1A1SMN1; SMN2REN | |
| SCHEMBL10173273 | 0.79 | ACE (0.55) | ACEALDH1A1SMN1; SMN2REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232849-B1 | PYRROLIDINEAMIDE DERIVATIVE OF ACYLAMINO ACID, PHARMACEUTICAL COMPOSITION AND USE | SUNTORY LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |
| US-5198458-A | Pyrrolidineamide derivatives of acylamino acid and pharmaceutical composition containing the same | SUNTORY LIMITED (JP) | 1993-03-30 | — | — | US | disclosed |
| US-4826870-A | CURING AMNESIA | SUNTORY LIMITED (JP) | 1989-05-02 | — | — | US | disclosed |