Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.55 |
| ▸ | NQO1 | P15559 | 1/20 | 0.52 |
| ▸ | ACACB | O00763 | 3/20 | 0.47 |
| ▸ | ACACA | Q13085 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502138 | 0.83 | LTA4H (0.57) | LTA4HNQO1ACACBACACATSHR | |
| SCHEMBL6285912 | 0.79 | NQO1 (0.82) | LTA4HNQO1TSHRTDP1SLC6A2 | |
| SCHEMBL12476726 | 0.79 | NQO1 (0.82) | LTA4HNQO1TSHRTDP1SLC6A2 | |
| SCHEMBL28184223 | 0.78 | NQO1 (0.64) | LTA4HNQO1ACACBTSHRTDP1 | |
| SCHEMBL28035026 | 0.76 | NQO1 (0.61) | LTA4HNQO1ACACBACACATSHR | |
| SCHEMBL3606244 | 0.76 | MIF (0.49) | TSHRTDP1L3MBTL1CA12CA1 | |
| SCHEMBL7315741 | 0.75 | LTA4H (0.38) | LTA4HACACBACACA | |
| SCHEMBL11520805 | 0.74 | NQO1 (0.52) | LTA4HNQO1TSHRTDP1PARP10 | |
| SCHEMBL6292553 | 0.74 | LTA4H (0.65) | LTA4HNQO1TSHRTDP1SLC6A2 | |
| SCHEMBL12188825 | 0.74 | NQO1 (0.64) | LTA4HNQO1ACACBTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186190-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-4663339-A | Acaricidal and insecticidal substituted 1-phenylalkylbenzimidazoles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-05-05 | — | — | US | disclosed |