Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | NQO1 | P15559 | 1/20 | 0.54 |
| ▸ | ACACB | O00763 | 9/20 | 0.51 |
| ▸ | ACACA | Q13085 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11737701 | 0.85 | ALDH1A1 (0.38) | LTA4HACACBACACATDP1TSHR | |
| SCHEMBL9501786 | 0.83 | LTA4H (0.55) | LTA4HNQO1ACACBACACATDP1 | |
| SCHEMBL12476726 | 0.81 | NQO1 (0.82) | LTA4HNQO1TDP1TSHRMAPT | |
| SCHEMBL6285912 | 0.81 | NQO1 (0.82) | LTA4HNQO1TDP1TSHRMAPT | |
| SCHEMBL7560598 | 0.78 | LTA4H (0.52) | LTA4HACACBACACATSHRHPGD | |
| SCHEMBL8036452 | 0.78 | NQO1 (0.61) | LTA4HNQO1ACACBACACATDP1 | |
| SCHEMBL12203937 | 0.77 | NQO1 (0.67) | LTA4HNQO1ACACBACACATDP1 | |
| SCHEMBL683602 | 0.77 | NQO1 (0.67) | LTA4HNQO1ACACBACACATDP1 | |
| SCHEMBL16596461 | 0.76 | LTA4H (0.61) | LTA4HNQO1ACACBACACATDP1 | |
| SCHEMBL2949090 | 0.76 | NQO1 (0.52) | LTA4HNQO1ACACBACACATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186190-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-4663339-A | Acaricidal and insecticidal substituted 1-phenylalkylbenzimidazoles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-05-05 | — | — | US | disclosed |
| EP-0186190-A2 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |