Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789108 | 0.77 | RAB9A (0.38) | PDE3BPDE3APDE2AMEN1KMT2A | |
| SCHEMBL9334583 | 0.65 | NPC1 (0.41) | PDE3BPDE3APDE2AMEN1KMT2A | |
| SCHEMBL8039845 | 0.65 | CDK5 (0.39) | KMT2AGAANPSR1MAPTSMN1; SMN2 | |
| SCHEMBL18493250 | 0.64 | RAB9A (0.35) | POLBNPSR1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL11799791 | 0.63 | NPC1 (0.36) | PDE3BPDE3APDE2AMEN1KMT2A | |
| SCHEMBL3859298 | 0.60 | NPC1 (0.41) | PDE3BPDE3APDE2AMEN1KMT2A | |
| SCHEMBL11055765 | 0.59 | ATM (0.49) | PDE3BPDE3AMEN1KMT2APOLB | |
| SCHEMBL16346102 | 0.58 | NPC1 (0.40) | PDE3BPDE3APDE2AMEN1KMT2A | |
| SCHEMBL862361 | 0.58 | PDE3B (0.49) | PDE3BPDE3APDE2ACYP1A2ALDH1A1 | |
| SCHEMBL355569 | 0.57 | BTK (0.39) | PDE3BPDE3APDE2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253276-B1 | PIGMENTS OF THE QUINACRIDONEQUINONE GROUP, THEIR PREPARATION PROCESS AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-21 | — | — | EP | disclosed |
| US-4881980-A | ACRIDONES INCORPORATED IN CRYSTAL LATTICE | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0253276-A2 | Pigments of the quinacridonequinone group, their preparation process and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-20 | — | — | EP | disclosed |