Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3669432 | 0.89 | RAB9A (0.57) | RAB9AGPR35PKMMAPTMEN1 | |
| SCHEMBL29162289 | 0.83 | RAB9A (0.59) | RAB9AGPR35PKMMAPTMEN1 | |
| SCHEMBL8748916 | 0.83 | RAB9A (0.52) | RAB9AGPR35PKMMAPTMEN1 | |
| SCHEMBL29566643 | 0.81 | MAPT (0.60) | RAB9AGPR35PKMMAPTMEN1 | |
| SCHEMBL308233 | 0.81 | MAPT (0.60) | RAB9AGPR35PKMMAPTMEN1 | |
| SCHEMBL309307 | 0.81 | RAB9A (0.51) | RAB9AGPR35PKMMAPTMEN1 | |
| SCHEMBL27988404 | 0.81 | RAB9A (0.51) | RAB9AGPR35PKMMAPTMEN1 | |
| SCHEMBL3041310 | 0.81 | RAB9A (0.51) | RAB9AGPR35PKMMAPTMEN1 | |
| SCHEMBL30120643 | 0.81 | RAB9A (0.48) | RAB9AGPR35PKMMAPTMEN1 | |
| SCHEMBL3666211 | 0.79 | POLB (0.46) | RAB9AMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018827-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL IN TREATMENT OF VALLINOID RECEPTOR TRPV1 RELATED DISORDERS | ASTRAZENECA AB (SE) | 2008-02-14 | — | — | WO | disclosed |
| US-5186717-A | Colorfastness, hair dyes | L'OREAL (FR) | 1993-02-16 | — | — | US | disclosed |