Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1894247 | 0.91 | GPR35 (0.49) | RAB9AGPR35CXCR2KCNMA1MAPT | |
| SCHEMBL3669432 | 0.90 | RAB9A (0.57) | RAB9AGPR35MAPTPKMMEN1 | |
| SCHEMBL29162289 | 0.84 | RAB9A (0.59) | RAB9AGPR35MAPTPKMMEN1 | |
| SCHEMBL309307 | 0.83 | RAB9A (0.51) | RAB9AGPR35MAPTPKMMEN1 | |
| SCHEMBL29566643 | 0.83 | MAPT (0.60) | RAB9AGPR35MAPTPKMMEN1 | |
| SCHEMBL9501876 | 0.83 | RAB9A (0.51) | RAB9AGPR35MAPTPKMMEN1 | |
| SCHEMBL3041310 | 0.83 | RAB9A (0.51) | RAB9AGPR35MAPTPKMMEN1 | |
| SCHEMBL308233 | 0.83 | MAPT (0.60) | RAB9AGPR35MAPTPKMMEN1 | |
| SCHEMBL27988404 | 0.83 | RAB9A (0.51) | RAB9AGPR35MAPTPKMMEN1 | |
| SCHEMBL15020230 | 0.82 | GPR35 (0.51) | GPR35CXCR2KCNMA1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659399-B1 | Process of direct hair using steam | OREAL (FR) | 1997-03-19 | — | — | EP | claimed |
| US-5496377-A | HAIR DYES, NITRO-AMINE COMPOUNDS | L'OREAL (FR) | 1996-03-05 | — | — | US | claimed |
| EP-0659399-A1 | Process of direct hair using steam | L'OREAL (FR) | 1995-06-28 | — | — | EP | claimed |
| CN-102481237-A | Hair dyeing method | KAO CORP | 2012-05-30 | — | — | CN | disclosed |
| EP-0659399-B1 | Process of direct hair using steam | OREAL (FR) | 1997-03-19 | — | — | EP | disclosed |
| US-5496377-A | HAIR DYES, NITRO-AMINE COMPOUNDS | L'OREAL (FR) | 1996-03-05 | — | — | US | disclosed |
| EP-0659399-A1 | Process of direct hair using steam | L'OREAL (FR) | 1995-06-28 | — | — | EP | disclosed |