Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10986286 | 0.87 | ALDH1A1 (0.54) | HPGDALDH1A1CYP3A4KMT2AMEN1 | |
| SCHEMBL27652976 | 0.81 | HPGD (0.47) | HPGDTDP1KMT2AMEN1NPC1 | |
| SCHEMBL3933947 | 0.79 | TDP1 (0.66) | HPGDALDH1A1TDP1KMT2AMEN1 | |
| Acetic Acid SCHEMBL9501909 | 0.77 | HPGD (0.58) | HPGDALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL29103969 | 0.77 | CYP3A4 (0.57) | HPGDALDH1A1CYP3A4KMT2AMEN1 | |
| SCHEMBL9501904 | 0.76 | HPGD (0.61) | HPGDALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL7692022 | 0.76 | HPGD (0.61) | HPGDALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL4204369 | 0.75 | HPGD (0.59) | HPGDALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL4192663 | 0.75 | HPGD (0.59) | HPGDALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL12251783 | 0.74 | HPGD (0.72) | HPGDTDP1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376852-B1 | MICROGRANULES ESSENTIALLY CONSISTING OF TRIGLYCERIDES OF SATURATED FATTY ACIDS LOADED WITH AN ACTIVE SUBSTANCE, AND THEIR TOPICAL THERAPEUTICAL USE | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1993-06-23 | — | — | EP | claimed |